Abstract
This pilot study used acoustic speech analysis to monitor patients with heart failure (HF), which is characterized by increased intracardiac filling pressures and peripheral edema. HF-related edema in the vocal folds and lungs is hypothesized to affect phonation and speech respiration. Acoustic measures of vocal perturbation and speech breathing characteristics were computed from sustained vowels and speech passages recorded daily from ten patients with HF undergoing inpatient diuretic treatment. After treatment, patients displayed a higher proportion of automatically identified creaky voice, increased fundamental frequency, and decreased cepstral peak prominence variation, suggesting that speech biomarkers can be early indicators of HF.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Acoustics*
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Aged
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Aged, 80 and over
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Diuretics / therapeutic use
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Edema / diagnosis*
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Edema / drug therapy
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Edema / etiology
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Edema / physiopathology
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Female
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Heart Failure / complications*
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Heart Failure / diagnosis
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Heart Failure / drug therapy
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Heart Failure / physiopathology
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Humans
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Lung / physiopathology
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Male
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Middle Aged
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Phonation* / drug effects
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Pilot Projects
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Predictive Value of Tests
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Respiration
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Speech Acoustics*
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Speech Production Measurement*
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Treatment Outcome
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Vocal Cords / drug effects
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Vocal Cords / physiopathology*
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Voice Disorders / diagnosis*
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Voice Disorders / drug therapy
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Voice Disorders / etiology
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Voice Disorders / physiopathology
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Voice Quality* / drug effects