Liver transplantation is the most effective salvage treatment for advanced liver failure, but its clinical application is limited by a shortage of liver donor, strict technology admittance, and complex and diverse issues in liver damage control before transplantation. We need to better understand the indications for liver transplantation in liver failure patients, select surgical timing correctly, and develop proper surgical regimens, in order to improve the rescue and cure rate of such patients. In addition, great achievements have been made in living-donor liver transplantation, auxiliary liver transplantation, and ABO-incompatible liver transplantation, which should be taken seriously in clinical practice.
肝移植是治疗中晚期肝功能衰竭最有效的挽救性治疗手段，但供肝来源匮乏、严格的技术准入以及移植前肝损害控制的复杂性、多样性等问题，限制其更有效地应用于临床。需要更好地把握肝衰竭患者肝移植的适应证，选择准确的手术时机，制定恰当的手术方案，以提高肝衰竭患者的救治率。另外，活体供肝肝移植、辅助性肝移植及ABO血型不相容肝移植等在肝衰竭治疗上的进展显著，值得关注和期待。.
Keywords: Immunosuppressive therapy; Liver failure; Liver transplantation; Selection criteria.