Gastric cancer diagnosis after presentation to the ED: The independent association of presenting location and outcomes

Am J Surg. 2018 Aug;216(2):286-292. doi: 10.1016/j.amjsurg.2017.10.030. Epub 2017 Nov 3.

Abstract

Background: The impact of diagnosis location on gastric cancer (GC) outcomes is poorly defined.

Methods: Detailed chart review was conducted to identify presenting location leading to diagnosis and treatment for GC patients at a single institution (2009-2013). Patients treated non-emergently following a diagnosis prompted by an ED visit (EDdx) were compared with those diagnosed at other locations (non-EDdx).

Results: EDdx patients comprised 52% of 263 GC patients. They were older, had later cancer stages (stage IV: 50% vs. 24%), more comorbidities (≥3: 68% vs. 47%), and presented with non-specific symptoms like bleeding (21% vs. 5%). Both groups were of similar race and insurance status. In a model adjusted for stage, EDdx was associated with increased mortality (aHR 1.9; 95% CI: 1.2-2.9).

Conclusion: Half of GC patients had an ED visit prompting diagnosis, which is independently associated with increased mortality. Efforts should focus on reducing EDdx rates to improve GC outcomes.

Keywords: Cancer diagnosis; Emergency department; Gastric cancer.

MeSH terms

  • Adenocarcinoma / diagnosis*
  • Adenocarcinoma / epidemiology
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Early Diagnosis*
  • Emergency Service, Hospital*
  • Female
  • Hospitalization / statistics & numerical data
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Neoplasm Staging / methods*
  • New York / epidemiology
  • Prognosis
  • Retrospective Studies
  • Stomach Neoplasms / diagnosis*
  • Stomach Neoplasms / epidemiology
  • Survival Rate / trends
  • Young Adult