Mesothelioma: Identical Routes to Malignancy from Asbestos and Carbon Nanotubes

Jennifer Port; Daniel J Murphy

doi:10.1016/j.cub.2017.07.026

Mesothelioma: Identical Routes to Malignancy from Asbestos and Carbon Nanotubes

Curr Biol. 2017 Nov 6;27(21):R1173-R1176. doi: 10.1016/j.cub.2017.07.026.

Authors

Jennifer Port¹, Daniel J Murphy²

Affiliations

¹ Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1BD, UK.
² Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1BD, UK; CRUK Beatson Institute for Cancer Research, University of Glasgow, Glasgow, G61 1BD, UK. Electronic address: [email protected].

PMID: 29112873
DOI: 10.1016/j.cub.2017.07.026

Abstract

Exposure of laboratory mice to carbon nanotubes mimics exposure to asbestos, from initial and chronic inflammation, through loss of the same tumour-suppressor pathways and eventual sporadic development of malignant mesothelioma. Fibres of a similar nature may pose significant health risks to humans.

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MeSH terms

Animals
Asbestos*
Humans
Inflammation
Lung Neoplasms*
Mesothelioma*
Mice
Nanotubes, Carbon*

Substances

Nanotubes, Carbon
Asbestos