[Chimerism analysis after hematopoietic cell transplantation: Guidelines from the Francophone Society of bone marrow transplantation and cellular therapy (SFGM-TC)]

Bull Cancer. 2017 Dec;104(12S):S59-S64. doi: 10.1016/j.bulcan.2017.08.010. Epub 2017 Nov 8.
[Article in French]

Abstract

Chimerism analysis is an important step for the patient follow-up after hematopoietic stem cell transplantation. It is used to quantify the donor and the recipient part of a cell population issued from blood or bone marrow sample. In addition to hemogram, this technique is necessary to appreciate the quality of engraftment. The aim of this article is to propose some recommendation about methods, result analysis and therapeutic decision in hematopoietic stem cell transplantation for malignant or non-malignant diseases.

Keywords: Blood; Chimerism; Chimérisme; Maladie résiduelle; Minimal residual disease; PCR quantitative; Real time PCR; Sang.

Publication types

  • Practice Guideline

MeSH terms

  • Allografts
  • Chimerism*
  • France
  • HLA Antigens / immunology
  • Hematologic Neoplasms / pathology
  • Hematologic Neoplasms / therapy*
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Microsatellite Repeats
  • Neoplasm, Residual
  • Societies, Medical

Substances

  • HLA Antigens