Cognitive impairment in neuromyelitis optica spectrum disorders: What do we know?

M B Eizaguirre; R Alonso; S Vanotti; O Garcea

doi:10.1016/j.msard.2017.10.003

Cognitive impairment in neuromyelitis optica spectrum disorders: What do we know?

Mult Scler Relat Disord. 2017 Nov:18:225-229. doi: 10.1016/j.msard.2017.10.003. Epub 2017 Oct 6.

Authors

M B Eizaguirre¹, R Alonso², S Vanotti², O Garcea²

Affiliations

¹ Demyelinating Diseases Section, J.M. Ramos Mejía Hospital, Buenos Aires, Argentina. Electronic address: [email protected].
² Demyelinating Diseases Section, J.M. Ramos Mejía Hospital, Buenos Aires, Argentina.

PMID: 29141815
DOI: 10.1016/j.msard.2017.10.003

Abstract

The aim of this study is to make a descriptive review of the bibliography available on cognitive dysfunction in patients with neuromyelitis optica spectrum disorders (NMOSD). We selected fifteen studies that quantitatively assess the relationship between NMOSD and one or more cognitive variables. Results showed that patients with NMOSD had a decrease in cognitive functions. Cognitive dysfunctions were found in 35-67% of patients with NMOSD, specifically in the attention, memory and information processing speed. Cognitive dysfunctions were found to relate to injuries in white matter as well as clinical variables and depression.

Keywords: Cognition; Cognitive disorders; Neuromyelitis optica.

Publication types

Review

MeSH terms

Animals
Cognitive Dysfunction / epidemiology
Cognitive Dysfunction / etiology*
Cognitive Dysfunction / physiopathology
Humans
Neuromyelitis Optica / complications*
Neuromyelitis Optica / epidemiology
Neuromyelitis Optica / physiopathology
Neuromyelitis Optica / psychology*