Rapid Assay for Detection of the Epidemiologically Important Central Asian/Russian Strain of the Mycobacterium tuberculosis Beijing Genotype

Igor Mokrousov; Ekaterina Chernyaeva; Anna Vyazovaya; Yuriy Skiba; Natalia Solovieva; Violeta Valcheva; Klavdia Levina; Natalya Malakhova; Wei-Wei Jiao; Lia Lima Gomes; Philip N Suffys; Marge Kütt; Nagima Aitkhozhina; A-Dong Shen; Olga Narvskaya; Viacheslav Zhuravlev

doi:10.1128/JCM.01551-17

Rapid Assay for Detection of the Epidemiologically Important Central Asian/Russian Strain of the Mycobacterium tuberculosis Beijing Genotype

J Clin Microbiol. 2018 Jan 24;56(2):e01551-17. doi: 10.1128/JCM.01551-17. Print 2018 Feb.

Authors

Igor Mokrousov¹, Ekaterina Chernyaeva², Anna Vyazovaya³, Yuriy Skiba⁴, Natalia Solovieva⁵, Violeta Valcheva^{6

7}, Klavdia Levina⁸, Natalya Malakhova⁴, Wei-Wei Jiao^{9

10

11

12}, Lia Lima Gomes¹³, Philip N Suffys¹³, Marge Kütt⁸, Nagima Aitkhozhina⁴, A-Dong Shen^{9

10

11

12}, Olga Narvskaya^{3

5}, Viacheslav Zhuravlev⁵

Affiliations

¹ Laboratory of Molecular Epidemiology and Evolutionary Genetics, St. Petersburg Pasteur Institute, St. Petersburg, Russia [email protected].
² Dobzhansky Center for Genome Bioinformatics, St. Petersburg State University, St. Petersburg, Russia.
³ Laboratory of Molecular Epidemiology and Evolutionary Genetics, St. Petersburg Pasteur Institute, St. Petersburg, Russia.
⁴ Laboratory of the Genome, Aitkhozhin Institute of Molecular Biology and Biochemistry, Almaty, Kazakhstan.
⁵ St. Petersburg Research Institute of Phthisiopulmonology, St. Petersburg, Russia.
⁶ Department of Infectious Microbiology, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
⁷ "In vitro" Laboratory for Evaluation of Biological Activity and Toxicity, Biopharmaceutical Laboratory Complex, Sofia Tech Park, Sofia, Bulgaria.
⁸ North Estonian Medical Centre Foundation, Tallinn, Estonia.
⁹ Beijing Key Laboratory of Pediatric Respiratory Infection Diseases, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
¹⁰ National Clinical Research Center for Respiratory Diseases, Beijing, China.
¹¹ National Key Discipline of Pediatrics, Capital Medical University, Beijing, China.
¹² Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China.
¹³ Fundação Oswaldo Cruz-Fiocruz, Laboratório de Biologia Molecular Aplicada a Micobactérias, Rio de Janeiro, RJ, Brazil.

No abstract available

Keywords: Beijing genotype; Central Asian outbreak; Mycobacterium tuberculosis; whole-genome sequencing.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Bacterial Proteins / genetics
DNA, Bacterial / genetics
Genetic Variation
Genotype
Molecular Diagnostic Techniques / methods*
Mycobacterium tuberculosis / genetics
Mycobacterium tuberculosis / isolation & purification*
Polymerase Chain Reaction*
Russia
Sigma Factor / genetics
Time Factors
Tuberculosis / diagnosis*
Tuberculosis / microbiology
Tuberculosis, Multidrug-Resistant / diagnosis
Tuberculosis, Multidrug-Resistant / microbiology

Substances

Bacterial Proteins
DNA, Bacterial
Sigma Factor
sigE protein, Bacteria