Epimetronomics: m6A Marks the Tempo of Corticogenesis

Nathan C Boles; Sally Temple

doi:10.1016/j.neuron.2017.11.002

Epimetronomics: m6A Marks the Tempo of Corticogenesis

Neuron. 2017 Nov 15;96(4):718-720. doi: 10.1016/j.neuron.2017.11.002.

Authors

Nathan C Boles¹, Sally Temple²

Affiliations

¹ Neural Stem Cell Institute, Rensselaer, NY 12144, USA. Electronic address: [email protected].
² Neural Stem Cell Institute, Rensselaer, NY 12144, USA. Electronic address: [email protected].

PMID: 29144970
DOI: 10.1016/j.neuron.2017.11.002

Abstract

Yoon et al. (2017) uncover a key role for the m6A RNA mark in regulating the timing of cerebral cortex development in mouse and human. This discovery opens new avenues of exploration into how the epitranscriptome helps orchestrate central nervous system formation.

Publication types

Comment

MeSH terms

Animals
Cerebral Cortex
Humans
Methylation
Mice
Neurogenesis*
Protein Processing, Post-Translational
RNA*

Substances

RNA