Diagnostic Accuracy of Parameters for Zika and Dengue Virus Infections, Singapore

Emerg Infect Dis. 2017 Dec;23(12):2085-2088. doi: 10.3201/eid2312.171224.

Abstract

Singapore experienced its first documented Zika virus outbreak in 2016. We identified clinical and laboratory parameters that increase the probability for Zika or dengue virus infection. Early during the illness, combinations of key parameters obtained through clinical assessment and hematologic tests can help distinguish between these infections.

Keywords: Aedes; Singapore; Zika virus; dengue; dengue virus; disease outbreaks; mosquitoes; vector-borne infections; viruses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Animals
  • Antigens, Viral / blood
  • Dengue / diagnosis
  • Dengue / epidemiology*
  • Dengue / immunology
  • Dengue / physiopathology
  • Dengue Virus / genetics*
  • Dengue Virus / immunology
  • Dengue Virus / isolation & purification
  • Diagnosis, Differential
  • Disease Outbreaks*
  • Exanthema / physiopathology
  • Female
  • Fever / physiopathology
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • RNA, Viral / blood
  • Singapore / epidemiology
  • Zika Virus / genetics*
  • Zika Virus / immunology
  • Zika Virus / isolation & purification
  • Zika Virus Infection / diagnosis
  • Zika Virus Infection / epidemiology*
  • Zika Virus Infection / immunology
  • Zika Virus Infection / physiopathology

Substances

  • Antigens, Viral
  • RNA, Viral