Giant Renal Angiomyolipoma Following Ovarian Stimulation Therapy

Urology. 2018 Feb:112:e3-e4. doi: 10.1016/j.urology.2017.10.039. Epub 2017 Nov 15.

Abstract

Renal angiomyolipomas (AMLs) are benign tumors with higher prevalence in women. Female hormones have been shown to induce AML enlargement. This case refers to a 40-year-old woman with 4 left kidney AMLs, the larger ones with 1.0 and 1.3 cm. Ten months after ovarian stimulation for egg harvesting, a computed tomography revealed an 18-cm AML with large-caliber vessels. Given her high risk of AML bleeding, the patient was submitted to selective arterial embolization, which turned out unsuccessful, supporting a plan of nephron-sparing surgery. Our case highlights the pro-growth effects of female hormones on AML, with particular emphasis to ovarian stimulation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angiomyolipoma / etiology*
  • Angiomyolipoma / pathology
  • Female
  • Humans
  • Kidney Neoplasms / etiology*
  • Kidney Neoplasms / pathology
  • Ovulation Induction / adverse effects*
  • Tumor Burden