Perfusion Imaging in Acute Traumatic Brain Injury

David B Douglas; Ruchir Chaudhari; Jason M Zhao; James Gullo; Jared Kirkland; Pamela K Douglas; Ely Wolin; James Walroth; Max Wintermark

doi:10.1016/j.nic.2017.09.002

Perfusion Imaging in Acute Traumatic Brain Injury

Neuroimaging Clin N Am. 2018 Feb;28(1):55-65. doi: 10.1016/j.nic.2017.09.002. Epub 2017 Oct 23.

Authors

David B Douglas¹, Ruchir Chaudhari², Jason M Zhao³, James Gullo³, Jared Kirkland³, Pamela K Douglas⁴, Ely Wolin³, James Walroth³, Max Wintermark⁵

Affiliations

¹ Department of Neuroradiology, Stanford University Medical Center, 300 Pasteur Drive, Room S047, Stanford, CA 94305-5105, USA; Department of Radiology, David Grant Medical Center, 101 Bodin Circle, Travis Air Force Base, CA 94535, USA.
² Department of Neuroradiology, Stanford University Medical Center, 300 Pasteur Drive, Room S047, Stanford, CA 94305-5105, USA.
³ Department of Radiology, David Grant Medical Center, 101 Bodin Circle, Travis Air Force Base, CA 94535, USA.
⁴ Institute for Simulation and Training, University of Central Florida, 3100 Technology Parkway, Orlando, FL 32826, USA.
⁵ Department of Neuroradiology, Stanford University Medical Center, 300 Pasteur Drive, Room S047, Stanford, CA 94305-5105, USA. Electronic address: [email protected].

Abstract

Traumatic brain injury (TBI) is a significant problem worldwide and neuroimaging plays a critical role in diagnosis and management. Recently, perfusion neuroimaging techniques have been explored in TBI to determine and characterize potential perfusion neuroimaging biomarkers to aid in diagnosis, treatment, and prognosis. In this article, computed tomography (CT) bolus perfusion, MR imaging bolus perfusion, MR imaging arterial spin labeling perfusion, and xenon CT are reviewed with a focus on their applications in acute TBI. Future research directions are also discussed.

Keywords: Concussion; Perfusion; TBI; Traumatic brain injury.

Publication types

Review

MeSH terms

Brain / diagnostic imaging
Brain Injuries / diagnostic imaging*
Diagnostic Imaging / methods*
Humans
Neuroimaging / methods
Perfusion Imaging / methods*

Abstract

Publication types

MeSH terms

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