Candida auris: an Emerging Fungal Pathogen

J Clin Microbiol. 2018 Jan 24;56(2):e01588-17. doi: 10.1128/JCM.01588-17. Print 2018 Feb.

Abstract

Candida auris has emerged globally as a multidrug-resistant health care-associated fungal pathogen. Recent reports highlight ongoing challenges due to organism misidentification, high rates of antifungal drug resistance, and significant patient mortality. The predilection for transmission within and between health care facilities possibly promoted by virulence factors that facilitate skin colonization and environmental persistence is unique among Candida species. This minireview details the global emergence of C. auris and discusses issues relevant to clinical microbiology laboratories, hospital infection control, and antimicrobial stewardship efforts.

Keywords: Candida auris; antifungal susceptibility; epidemiology; infection control.

Publication types

  • Review

MeSH terms

  • Antifungal Agents / administration & dosage
  • Antifungal Agents / pharmacology
  • Antimicrobial Stewardship
  • Candida / drug effects
  • Candida / isolation & purification
  • Candida / pathogenicity
  • Candida / physiology*
  • Candidiasis / drug therapy
  • Candidiasis / epidemiology*
  • Candidiasis / microbiology
  • Candidiasis / prevention & control*
  • Clinical Laboratory Techniques
  • Cross Infection / epidemiology
  • Cross Infection / prevention & control
  • Drug Resistance, Fungal / genetics
  • Humans
  • Skin / microbiology
  • Virulence Factors

Substances

  • Antifungal Agents
  • Virulence Factors