This article critically reviews the latest evidence to guide the use of biomarkers for the diagnosis of acute coronary syndromes in practice. It shows how modern cardiac troponin assays can enable diagnoses to be ruled in or ruled out with a single blood test, with many more diagnoses confirmed or refuted in as little as 1 hour later. Finally, this article appraises the latest evidence for other cardiac biomarkers, such as heart-type fatty acid-binding protein and copeptin.
Keywords: Acute coronary syndromes; Biomarkers; Sensitivity and specificity; Troponin.
Copyright © 2017 Elsevier Inc. All rights reserved.