Anodal transcranial direct current stimulation over left inferior frontal gyrus enhances sentence comprehension

Brain Lang. 2018 Jan:176:36-41. doi: 10.1016/j.bandl.2017.11.001. Epub 2017 Nov 23.

Abstract

We tested the possibility of enhancing natural language comprehension through the application of anodal tDCS (a-tDCS) over the left inferior frontal gyrus, a key region for verbal short-term memory and language comprehension. We designed a between subjects sham- and task-controlled study. During tDCS stimulation, participants performed a sentence to picture matching task in which targets were sentences with different load on short-term memory. Regardless of load on short-term memory, the Anodal group performed significantly better than the Sham group, thus providing evidence that a-tDCS over LIFG enhances natural language comprehension. To our knowledge, we apply for the first time tDCS to boost sentence comprehension. This result is of special interest also from a clinical perspective: applying a-tDCS in patients manifesting problems at the sentence level due to brain damage could enhance the effects of behavioral rehabilitation procedures aimed to improve language comprehension.

Keywords: Left inferior frontal gyrus; Sentence comprehension; Verbal short-term memory; tDCS.

MeSH terms

  • Acoustic Stimulation / methods*
  • Comprehension / physiology*
  • Electrodes
  • Female
  • Humans
  • Language Tests
  • Language*
  • Male
  • Memory, Short-Term / physiology
  • Photic Stimulation / methods*
  • Prefrontal Cortex / physiology*
  • Transcranial Direct Current Stimulation / methods*
  • Young Adult