Resectability and Vascular Management of Retroperitoneal Gynecological Malignancies: A Large Single-institution Case-Series

Anticancer Res. 2017 Dec;37(12):6899-6906. doi: 10.21873/anticanres.12153.

Abstract

Background/aim: To report on morbidity and oncological outcomes in a consecutive series of gynecological malignancies involving the vascular district.

Patients and methods: We retrospectively evaluated a consecutive series between 1/2015 and 1/2017 with suspicious gynecological malignancies involving the vascular district. Peri-operative data and survival rates were computed.

Results: Eight-hundred-four women with gynecological malignancies were admitted for major oncologic surgery during the study period, and among them, 50 cases (6.2%) showed vascular involvement. Twenty-seven and 23 patients were submitted to minor and major vascular procedures, respectively. R0 resection was achieved in 44 patients. There were no perioperative mortalities. Major postoperative complications occurred in 6 patients (12.0%). The 2-year disease free survival (DFS) was 67% if R0 resection was achieved. In patients with positive pathological margins (n=2), the 2-year DFS was 33%.

Conclusion: Vascular procedures can be safely performed with a proper pre-operative planning and may not be an impediment to major gynecological oncological surgery.

Keywords: Vascular resection; gynecological malignancies; post-operative complications.

MeSH terms

  • Abscess / diagnosis
  • Abscess / etiology
  • Adult
  • Aged
  • Female
  • Genital Neoplasms, Female / blood supply
  • Genital Neoplasms, Female / surgery*
  • Humans
  • Kaplan-Meier Estimate
  • Middle Aged
  • Pelvic Infection / diagnosis
  • Pelvic Infection / etiology
  • Postoperative Complications / diagnosis*
  • Postoperative Complications / etiology
  • Retroperitoneal Neoplasms / blood supply
  • Retroperitoneal Neoplasms / surgery*
  • Retrospective Studies
  • Vascular Surgical Procedures / adverse effects
  • Vascular Surgical Procedures / methods*
  • Young Adult