Continuous vancomycin in a pediatric cystic fibrosis patient

Pediatr Pulmonol. 2018 Jan;53(1):E4-E5. doi: 10.1002/ppul.23844. Epub 2017 Nov 29.

Abstract

Continuous vancomycin has been previously reported to maximize antimicrobial activity while avoiding toxicities associated with dose escalation, but the efficacy of this dosing strategy has not been reported. This case report describes the successful use of continuous vancomycin, including improvement in lung function and avoidance of nephrotoxicity, demonstrated in a pediatric cystic fibrosis (CF) patient with MRSA.

Keywords: MRSA; cystic fibrosis; vancomycin.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Child
  • Cystic Fibrosis / drug therapy*
  • Female
  • Humans
  • Methicillin-Resistant Staphylococcus aureus*
  • Staphylococcal Infections / drug therapy*
  • Vancomycin / therapeutic use*

Substances

  • Anti-Bacterial Agents
  • Vancomycin