UTR-Dependent Control of Gene Expression in Plants

Trends Plant Sci. 2018 Mar;23(3):248-259. doi: 10.1016/j.tplants.2017.11.003. Epub 2017 Dec 6.

Abstract

Throughout their lives, plants sense many developmental and environmental stimuli, and activation of optimal responses against these stimuli requires extensive transcriptional reprogramming. To facilitate this activation, plant mRNA contains untranslated regions (UTRs) that significantly increase the coding capacity of the genome by producing multiple mRNA variants from the same gene. In this review we compare UTRs of arabidopsis (Arabidopsis thaliana) and rice (Oryza sativum) at the genome scale to highlight their complexity in crop plants. We discuss different modes of UTR-based regulation with emphasis on genes that regulate multiple plant processes, including flowering, stress responses, and nutrient homeostasis. We demonstrate functional specificity in genes with variable UTR length and propose future research directions.

Keywords: adenosine methylation; alternative splicing; epigenetics; nonsense-mediated decay; polyadenylation; riboswitch.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Arabidopsis / genetics
  • Arabidopsis / physiology
  • Gene Expression / genetics*
  • Gene Expression Regulation, Plant / genetics*
  • Gene Expression Regulation, Plant / physiology
  • Genome, Plant / genetics
  • Oryza / genetics
  • Oryza / physiology
  • RNA, Messenger / genetics
  • RNA, Plant / genetics*
  • Riboswitch / genetics
  • Riboswitch / physiology
  • Untranslated Regions / genetics*

Substances

  • RNA, Messenger
  • RNA, Plant
  • Riboswitch
  • Untranslated Regions