Does a third arterial conduit to the right coronary circulation improve survival?

J Thorac Cardiovasc Surg. 2018 Mar;155(3):855-860.e2. doi: 10.1016/j.jtcvs.2017.09.163. Epub 2017 Nov 21.

Abstract

Background: The long-term benefits of a third arterial conduit to the right circulation in triple-vessel disease remain debatable. This retrospective, single-center, propensity-matched study investigates the impact of a third arterial conduit to the right circulation on early and intermediate survival after coronary artery bypass grafting.

Methods: Data were retrospectively collected from 2004 to 2014 for all surgical revascularizations for triple-vessel disease with at least 2 arterial conduits to the left circulation and a third arterial or venous conduit to the right circulation. A total of 167 pairs were propensity matched to arterial versus venous third conduit to right circulation. Hazard functions were obtained with Cox multivariate regression and Kaplan-Meier survival curves were compared between the matched cohorts.

Results: Extracardiac arteriopathy, logistic euroSCORE, and left main stem disease were significant predictors of adverse survival. A third arterial conduit to the right circulation was not a significant predictor of improved survival in multivariate analysis (HR, 0.72; 95% CI, 0.34-1.55; P = .411). 30-day mortality was 0.6% in both groups. There was no significant difference in early or intermediate survival in the propensity-matched groups (venous vs arterial, 99.2% vs 99.2%; P = 1.000 at 1 year; 85.2% vs 88.8%; P = .248 at 5 years and 69.2% vs 88.8%; P = .297 at 7 years) CONCLUSIONS: The use of a third arterial versus a venous conduit to the right circulation does not improve early or intermediate survival up to 7 years in triple-vessel coronary artery disease in this study. Longer follow-up and larger cohorts may be needed for differences to emerge.

Keywords: arterial conduits; bypass; coronary; right circulation.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Coronary Artery Bypass / adverse effects
  • Coronary Artery Bypass / methods*
  • Coronary Artery Bypass / mortality
  • Coronary Artery Disease / diagnostic imaging
  • Coronary Artery Disease / mortality
  • Coronary Artery Disease / physiopathology
  • Coronary Artery Disease / surgery*
  • Coronary Circulation*
  • Coronary Vessels / diagnostic imaging
  • Coronary Vessels / physiopathology
  • Coronary Vessels / surgery*
  • Female
  • Humans
  • Male
  • Mammary Arteries / diagnostic imaging
  • Mammary Arteries / physiopathology
  • Mammary Arteries / transplantation*
  • Middle Aged
  • Radial Artery / diagnostic imaging
  • Radial Artery / physiopathology
  • Radial Artery / transplantation*
  • Retrospective Studies
  • Risk Assessment
  • Risk Factors
  • Time Factors
  • Treatment Outcome