Identification of Germline Variants in Tumor Genomic Sequencing Analysis

Nathan D Montgomery; Sara R Selitsky; Nirali M Patel; D Neil Hayes; Joel S Parker; Karen E Weck

doi:10.1016/j.jmoldx.2017.09.008

Identification of Germline Variants in Tumor Genomic Sequencing Analysis

J Mol Diagn. 2018 Jan;20(1):123-125. doi: 10.1016/j.jmoldx.2017.09.008.

Authors

Nathan D Montgomery¹, Sara R Selitsky², Nirali M Patel¹, D Neil Hayes², Joel S Parker², Karen E Weck³

Affiliations

¹ Department of Pathology and Laboratory Medicine, The University of North Carolina School of Medicine, Chapel Hill, North Carolina; Lineberger Comprehensive Cancer Center, The University of North Carolina School of Medicine, Chapel Hill, North Carolina.
² Lineberger Comprehensive Cancer Center, The University of North Carolina School of Medicine, Chapel Hill, North Carolina.
³ Department of Pathology and Laboratory Medicine, The University of North Carolina School of Medicine, Chapel Hill, North Carolina; Lineberger Comprehensive Cancer Center, The University of North Carolina School of Medicine, Chapel Hill, North Carolina. Electronic address: [email protected].

PMID: 29249243
DOI: 10.1016/j.jmoldx.2017.09.008

Abstract

This Correspondence relates to the article by Li et al (Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer: A Joint Consensus Recommendation of the Association for Molecular Pathology, American Society of Clinical Oncology, and the College of American Pathologists. J Mol Diagn 2017, 19:4-23).

Publication types

Letter
Comment

MeSH terms

Alleles
Cohort Studies
Genomics / methods*
Germ-Line Mutation / genetics*
Guidelines as Topic
Humans
Neoplasms / genetics*
Sequence Analysis, DNA / methods*