Mutations and karyotype in myelodysplastic syndromes: TP53 clusters with monosomal karyotype, RUNX1 with trisomy 21, and SF3B1 with inv(3)(q21q26.2) and del(11q)

Blood Cancer J. 2017 Dec 18;7(12):658. doi: 10.1038/s41408-017-0017-8.
No abstract available

Publication types

  • Letter

MeSH terms

  • Abnormal Karyotype
  • Adult
  • Aged
  • Aged, 80 and over
  • Core Binding Factor Alpha 2 Subunit / genetics*
  • Down Syndrome / genetics
  • Female
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Karyotyping
  • Male
  • Middle Aged
  • Mutation
  • Myelodysplastic Syndromes / genetics*
  • Myelodysplastic Syndromes / mortality
  • Phosphoproteins / genetics*
  • RNA Splicing Factors / genetics*
  • Survival Analysis
  • Tumor Suppressor Protein p53 / genetics*

Substances

  • Core Binding Factor Alpha 2 Subunit
  • Phosphoproteins
  • RNA Splicing Factors
  • RUNX1 protein, human
  • SF3B1 protein, human
  • TP53 protein, human
  • Tumor Suppressor Protein p53