A Posterior Circulation Ischemia Risk Score System to Assist the Diagnosis of Dizziness

J Stroke Cerebrovasc Dis. 2018 Feb;27(2):506-512. doi: 10.1016/j.jstrokecerebrovasdis.2017.09.027. Epub 2017 Dec 15.

Abstract

Background: We aimed to establish a risk score system without radio-image examination, which could help clinicians to differentiate patients with vertigo and posterior circulation ischemia (PCI) rapidly from the other dizzy patients.

Methods: We analyzed 304 patients with vertigo (50% PCI). The attributes with more significant contributions were selected as the risk factors for the PCI risk score system, and every one of them was assigned a value according to their respective odds ratio values. We also compared the respective receiver operating characteristic curves of the 3 diagnostic methods (PCI score system, ABCD2, and Essen score systems) to evaluate their prediction effectiveness.

Results: Nine risk factors were ultimately selected for PCI score system, including high blood pressure (1'), diabetes mellitus (1'), ischemic stroke (1'), rotating and rocking (-1'), difficulty in speech (5'), tinnitus (-5'), limb and sensory deficit (5'), gait ataxia (1'), and limb ataxia (5'). According to their respective PCI risk scores, the patients were divided into 3 subgroups: low risk (≤0', risk <37.4%), medium risk (1'-5'), and high risk (≥6', risk >95.0%). When 0' was selected as a cutoff point for differentiating the patients with PCI from patients without PCI, the sensitivity was 94.1%, with a specificity of 41.4%. The areas under the receiver operator curve value of PCI score system was .82 (P = .000), much higher than the areas under the receiver operator curve value of ABCD2 (.69, P = .000) and that of the Essen system (.67, P = .000) CONCLUSION: The PCI score system could help clinicians to differentiate patients with vertigo and PCI rapidly from the other dizzy patients.

Keywords: Dizziness or vertigo; diagnosis; physical examination; posterior circulation ischemia; risk scores.

MeSH terms

  • Aged
  • Area Under Curve
  • Decision Support Techniques*
  • Diagnosis, Differential
  • Dizziness / etiology*
  • Dizziness / physiopathology
  • Female
  • Humans
  • Infarction, Posterior Cerebral Artery / complications
  • Infarction, Posterior Cerebral Artery / diagnosis*
  • Infarction, Posterior Cerebral Artery / physiopathology
  • Logistic Models
  • Male
  • Middle Aged
  • Odds Ratio
  • Predictive Value of Tests
  • Preliminary Data
  • ROC Curve
  • Reproducibility of Results
  • Retrospective Studies
  • Risk Factors
  • Vertigo / complications
  • Vertigo / diagnosis*
  • Vertigo / physiopathology