L-671,329, a new antifungal agent. II. Structure determination

J Antibiot (Tokyo). 1989 Feb;42(2):168-73. doi: 10.7164/antibiotics.42.168.

Abstract

Based on spectroscopic data L-671,329, isolated from a filamentous fungus ATCC 20868, has been assigned the structure 1. The compound is a lipopeptide antifungal agent and a structural analog of echinocandin B.

MeSH terms

  • Amino Acid Sequence
  • Amino Acids / analysis
  • Anti-Bacterial Agents*
  • Antifungal Agents*
  • Echinocandins
  • Fungal Proteins*
  • Gas Chromatography-Mass Spectrometry
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Molecular Structure
  • Peptides
  • Peptides, Cyclic
  • Spectrophotometry, Ultraviolet

Substances

  • Amino Acids
  • Anti-Bacterial Agents
  • Antifungal Agents
  • Echinocandins
  • Fungal Proteins
  • Peptides
  • Peptides, Cyclic
  • pneumocandin A(0)
  • echinocandin B