Pyruvate Kinase and Warburg Metabolism in Pulmonary Arterial Hypertension: Uncoupled Glycolysis and the Cancer-Like Phenotype of Pulmonary Arterial Hypertension

Circulation. 2017 Dec 19;136(25):2486-2490. doi: 10.1161/CIRCULATIONAHA.117.031655.
No abstract available

Keywords: DNA methylation; Editorials; bone morphogenetic protein receptors, type II; extracellular signal-related MAP kinases; glycolysis.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Endothelial Cells
  • Glycolysis
  • Heterogeneous-Nuclear Ribonucleoproteins
  • Humans
  • Hypertension, Pulmonary*
  • MicroRNAs
  • Neoplasms*
  • Phenotype
  • Polypyrimidine Tract-Binding Protein
  • Pyruvate Kinase

Substances

  • Heterogeneous-Nuclear Ribonucleoproteins
  • MIRN124 microRNA, human
  • MicroRNAs
  • PTBP1 protein, human
  • Polypyrimidine Tract-Binding Protein
  • Pyruvate Kinase