I Remember You: Epigenetic Priming in Epithelial Stem Cells

Boris Novakovic; Hendrik G Stunnenberg

doi:10.1016/j.immuni.2017.12.005

I Remember You: Epigenetic Priming in Epithelial Stem Cells

Immunity. 2017 Dec 19;47(6):1019-1021. doi: 10.1016/j.immuni.2017.12.005.

Authors

Boris Novakovic¹, Hendrik G Stunnenberg²

Affiliations

¹ Department of Molecular Biology, Radboud Institute of Molecular Life Sciences and Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands.
² Department of Molecular Biology, Radboud Institute of Molecular Life Sciences and Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands. Electronic address: [email protected].

PMID: 29262345
DOI: 10.1016/j.immuni.2017.12.005

Abstract

Exposure to inflammatory stimuli can remodel immune cells in a way that alters their response to future insults. In a landmark paper in Nature, Elaine Fuchs and colleagues show that memory of inflammation is not restricted to the hematopoietic lineage (Naik et al., 2017).

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MeSH terms

Epigenesis, Genetic
Epigenomics*
Humans
Inflammation
Skin
Stem Cells*