Sensitive PCR-based monitoring and early detection of relapsed JAK2 V617F myelofibrosis following transplantation

Br J Haematol. 2018 Dec;183(5):831-835. doi: 10.1111/bjh.15059. Epub 2017 Dec 19.

Authors

Mithun V Shah¹, Keyur P Patel², Raja Luthra², Rashmi Kanagal-Shamanna², Meenakshi Mehrotra², Lohith S Bachegowda¹, Richard E Champlin¹, Srdan Verstovsek³, Uday R Popat¹

Affiliations

¹ Department of Stem Cell Transplantation and Cellular Therapy, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
² Department of Hematopathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
³ Department of Leukemia, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.

PMID: 29265180
DOI: 10.1111/bjh.15059

No abstract available

Keywords: allogeneic hematopoietic stem cell transplantation; minimal residual disease; myelofibrosis.

Publication types

Letter

MeSH terms

Adult
Aged
Biomarkers / metabolism
Early Diagnosis
Female
Hematopoietic Stem Cell Transplantation
Humans
Janus Kinase 2 / genetics
Janus Kinase 2 / metabolism*
Male
Middle Aged
Primary Myelofibrosis / diagnosis*
Primary Myelofibrosis / therapy
Real-Time Polymerase Chain Reaction / methods
Recurrence
Sensitivity and Specificity
Time Factors

Substances

Biomarkers
JAK2 protein, human
Janus Kinase 2