Dynamic Observation of the Morphological Changes in Paraurethral Ducts Infected with Gonococci in Men before and after Ceftriaxone Therapy Using High-Frequency Ultrasound

Urol Int. 2018;100(2):240-244. doi: 10.1159/000484697. Epub 2017 Dec 22.

Abstract

Objective: To observe the morphological changes in paraurethral ducts infected with gonococci in men before and after the administration of the ceftriaxone therapy using high-frequency ultrasound and determine its clinical significance.

Methods: Thirty-two male patients with gonococcal paraurethral duct infection were enrolled. Their lesions were examined using an ACUSON X300 ultrasound system before and after they were subjected to ceftriaxone therapy.

Results: The paraurethral duct was completely closed 3-4 days after ceftriaxone treatment in 30 patients. Paraurethral duct closure began from the blind end and proceeded gradually towards its orifice; during closure, the paraurethral duct diameter showed no apparent change. These 30 patients whose paraurethral ducts closed were considered cured. In the remaining 2 patients, the length and diameter of the paraurethral ducts showed no change before and after ceftriaxone treatment; one patient was unresponsive to ceftriaxone treatment, and the other had secondary dilatation of the paraurethral duct. These 2 patients were cured after surgery.

Conclusion: High-frequency ultrasound enables dynamic observation of the morphological changes in paraurethral ducts infected with gonococci before and after ceftriaxone therapy. High-frequency ultrasound can provide valuable information for incision, drainage, and wedge resection of paraurethral ducts.

Keywords: Dynamic observation; High-frequency ultrasound; Men; Neisseria gonorrhoeae; Paraurethral duct.

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use*
  • Ceftriaxone / therapeutic use*
  • Gonorrhea / diagnostic imaging
  • Gonorrhea / drug therapy*
  • Gonorrhea / microbiology
  • Humans
  • Male
  • Middle Aged
  • Neisseria gonorrhoeae / drug effects*
  • Neisseria gonorrhoeae / isolation & purification
  • Predictive Value of Tests
  • Time Factors
  • Treatment Outcome
  • Ultrasonography*
  • Urethra / diagnostic imaging
  • Urethra / drug effects*
  • Urethra / microbiology
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Ceftriaxone