Neurological disease may precede lymphadenopathies in Actinomyces europaeus infection

J Infect Public Health. 2018 Jul-Aug;11(4):592-593. doi: 10.1016/j.jiph.2017.12.010. Epub 2017 Dec 23.

Abstract

Actinomyces species are part of the commensal flora of the mucous membranes of the oropharynx, gastrointestinal tract and female genital tract. Actinomyces europaeus is a short, nonmotile, facultative anaerobic rod first described in 1997, susceptible in vitro to a wide range of b-lactam antibiotics which are regarded as first choice. In this report we described the case of A. europaeus infection in a young female patient admitted to Intensive Care Unit and the possible damage of vascular endothelium due to a chronic progressive actinomycosis that at first involved neck soft tissue, then cervical lymphnodes, and finally extended to the vascular structure.

Keywords: Actinomyces; Actinomycosis; Intensive care unit; Neurological symptoms; Vascular infections; Vasculitis.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Actinomyces / drug effects
  • Actinomyces / genetics
  • Actinomyces / isolation & purification
  • Actinomycosis / diagnosis*
  • Actinomycosis / drug therapy
  • Actinomycosis / immunology
  • Anti-Bacterial Agents / therapeutic use
  • Brain / diagnostic imaging
  • Endothelium, Vascular / microbiology
  • Endothelium, Vascular / pathology
  • Female
  • Humans
  • Intensive Care Units
  • Lymph Nodes / microbiology
  • Lymphadenopathy / diagnosis
  • Lymphadenopathy / diagnostic imaging
  • Lymphadenopathy / drug therapy
  • Lymphadenopathy / microbiology*
  • Nervous System Diseases / complications*
  • Nervous System Diseases / microbiology
  • RNA, Ribosomal, 16S
  • Symbiosis
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Vasculitis / microbiology
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • RNA, Ribosomal, 16S