Serious neuropsychiatric adverse effects related to interaction between itraconazole and darunavir/ritonavir in an HIV-infected patient with cerebral histoplasmosis

J Antimicrob Chemother. 2018 Apr 1;73(4):1108-1110. doi: 10.1093/jac/dkx495.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Anti-HIV Agents / administration & dosage
  • Anti-HIV Agents / adverse effects*
  • Antifungal Agents / administration & dosage
  • Antifungal Agents / adverse effects*
  • Darunavir / administration & dosage
  • Darunavir / adverse effects*
  • Drug Interactions*
  • HIV Infections / complications
  • HIV Infections / drug therapy
  • Histoplasmosis / complications
  • Histoplasmosis / drug therapy
  • Humans
  • Itraconazole / administration & dosage
  • Itraconazole / adverse effects*
  • Male
  • Mental Disorders / chemically induced*
  • Mental Disorders / diagnosis
  • Mental Disorders / pathology
  • Middle Aged
  • Plasma / chemistry
  • Ritonavir / administration & dosage
  • Ritonavir / adverse effects*

Substances

  • Anti-HIV Agents
  • Antifungal Agents
  • Itraconazole
  • Ritonavir
  • Darunavir