The alkylation of alcohols and polyols has been investigated with alkylphosphates in the presence of a Lewis or Brønsted acid catalyst. The permethylation of polyols was developed under solvent-free conditions at 100 °C with either iron triflate or Aquivion PW98, affording the isolated products in yields between 52 and 95 %. The methodology was also adjusted to carry out peralkylation with longer alkyl chains.
Keywords: Brønsted acids; alkylation; methylation; phosphates; polyols.
© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.