Stenting of the inter-atrial septum in infants and small children: Indications, techniques and outcomes

Catheter Cardiovasc Interv. 2018 Jun;91(7):1294-1300. doi: 10.1002/ccd.27462. Epub 2018 Jan 11.

Abstract

Objectives: To evaluate the procedural success and outcome of inter-atrial stenting.

Background: Inter-atrial stenting has been shown to be an effective way to maintain inter-atrial blood flow, however it is considered a high risk procedure, usually performed urgently in patients with significant hemodynamic compromise.

Methods: Between September 2004 and August 2016, inter-atrial stenting was attempted in 29 children. Procedural, clinical, and follow-up data were collected retrospectively.

Results: The procedures were completed successfully in 27 patients. Twenty-five procedures were undertaken percutaneously, with the remaining four being performed as hybrid procedures. The patients were considered as high risk for adverse events (82% scored as CRISP 4 and 5) with four deaths during the first 24 hr (14%). Procedural complications occurred in eight patients (28%) with related death in three patients (10%). One further patient died after an uncomplicated technically successful stent implantation performed as a salvage procedure. Procedural complications (71% vs. 14%) and mortality (43% vs. 5%) were higher in those, who weighed 3 kg or less (P < 0.05). Patency of the stents was maintained until planned staged surgery in 22 patients at a mean of 302 days. Three patients underwent further balloon dilation for flow restriction at 58-201 days. In two un-operated patients the stents remained patent at follow-up. One patient with severe pulmonary hypertension died with a patent stent.

Conclusions: Inter-atrial stenting produces reliable patency with a very good success rate. Morbidity and mortality were related to low weight at the time of the procedure.

Keywords: CONP (congenital heart disease; SHDI (structural heart disease intervention); STEC (stenting technique); pediatrics).

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Age Factors
  • Atrial Septum* / diagnostic imaging
  • Atrial Septum* / physiopathology
  • Cardiac Catheterization / adverse effects
  • Cardiac Catheterization / instrumentation*
  • Cardiac Catheterization / mortality
  • Child
  • Child, Preschool
  • Echocardiography, Doppler, Color
  • Echocardiography, Transesophageal
  • Female
  • Heart Defects, Congenital / diagnostic imaging
  • Heart Defects, Congenital / physiopathology
  • Heart Defects, Congenital / therapy*
  • Humans
  • Infant
  • Infant, Newborn
  • London
  • Male
  • Poland
  • Radiography, Interventional
  • Retrospective Studies
  • Risk Factors
  • Stents*
  • Treatment Outcome
  • Ultrasonography, Interventional