Mother's age at menopause but not own age at menarche has an impact on ovarian reserve

Gynecol Endocrinol. 2018 Aug;34(8):664-665. doi: 10.1080/09513590.2018.1428300. Epub 2018 Jan 18.

Abstract

To detect clinical parameters impacting ovarian reserve, data were analyzed from 573 patients who had an anti-Müllerian hormone (AMH) measurement for infertility treatment. No impact was found on the age at menarche but a significant diminished ovarian reserve was observed when a patient's mother was menopausal before age 50. These data suggest that ovarian reserve must be monitored in such patients to offer them fertility preservation when at risk of premature ovarian insufficiency (POI).

Keywords: AMH; menarche; menopause; premature ovarian insufficiency.

MeSH terms

  • Adult
  • Anti-Mullerian Hormone / blood*
  • Female
  • Humans
  • Maternal Age
  • Menarche
  • Menopause*
  • Ovarian Reserve*
  • Primary Ovarian Insufficiency / blood*

Substances

  • Anti-Mullerian Hormone