Partial tandem duplication of KMT2A (MLL) may predict a subset of myelodysplastic syndrome with unique characteristics and poor outcome

Haematologica. 2018 Mar;103(3):e131-e134. doi: 10.3324/haematol.2017.185249. Epub 2018 Jan 19.

Authors

Sarah M Choi¹, Rajan Dewar², Patrick W Burke³, Lina Shao²

Affiliations

¹ Department of Pathology, University of Michigan, Ann Arbor, MI, USA [email protected].
² Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
³ Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.

No abstract available

MeSH terms

Adult
Aged
Female
Gene Duplication*
Histone-Lysine N-Methyltransferase / genetics*
Humans
Male
Middle Aged
Myelodysplastic Syndromes / classification*
Myelodysplastic Syndromes / diagnosis
Myelodysplastic Syndromes / mortality
Myelodysplastic Syndromes / therapy
Myeloid-Lymphoid Leukemia Protein / genetics*
Predictive Value of Tests
Prognosis
Survival Analysis
Treatment Outcome

Substances

KMT2A protein, human
Myeloid-Lymphoid Leukemia Protein
Histone-Lysine N-Methyltransferase