Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors

Biochim Biophys Acta Gene Regul Mech. 2018 Feb;1861(2):147-157. doi: 10.1016/j.bbagrm.2018.01.010. Epub 2018 Jan 31.

Authors

Affiliations

¹ Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.
² Department of Molecular Cell Biology of Plants, Faculty of Biosciences, Goethe-University Frankfurt, 60438 Frankfurt, Germany.
³ Functional Proteomics, SFB 815 Core Unit, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.
⁴ Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany. Electronic address: [email protected].

PMID: 29378331
DOI: 10.1016/j.bbagrm.2018.01.010

No abstract available

Keywords: Cap-independent translation; IRES trans-acting factor; Internal ribosome entry site; RNA-binding protein; TXNIP.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

5' Untranslated Regions / genetics*
Blotting, Western
Carrier Proteins / genetics*
Carrier Proteins / metabolism
DNA-Binding Proteins / genetics
DNA-Binding Proteins / metabolism
Humans
Internal Ribosome Entry Sites / genetics*
MCF-7 Cells
Polypyrimidine Tract-Binding Protein / genetics
Polypyrimidine Tract-Binding Protein / metabolism
Protein Binding
Protein Biosynthesis*
RNA Interference
Ribonucleoproteins, Small Nuclear / genetics
Ribonucleoproteins, Small Nuclear / metabolism
SMN Complex Proteins
Transcription Factors / genetics
Transcription Factors / metabolism

Substances

5' Untranslated Regions
Carrier Proteins
DNA-Binding Proteins
FUBP3 protein, human
GEMIN5 protein, human
Internal Ribosome Entry Sites
Ribonucleoproteins, Small Nuclear
SMN Complex Proteins
TXNIP protein, human
Transcription Factors
Polypyrimidine Tract-Binding Protein