The important role of co-infections in patients with AIDS and progressive disseminated histoplasmosis (PDH): A cohort from Colombia

Diego H Caceres; Ángela M Tobón; Ángela Restrepo; Tom Chiller; Beatriz L Gómez

doi:10.1016/j.mmcr.2017.07.004

The important role of co-infections in patients with AIDS and progressive disseminated histoplasmosis (PDH): A cohort from Colombia

Med Mycol Case Rep. 2018 Jan 17:19:41-44. doi: 10.1016/j.mmcr.2017.07.004. eCollection 2018 Mar.

Authors

Diego H Caceres¹, Ángela M Tobón^{1

2}, Ángela Restrepo¹, Tom Chiller³, Beatriz L Gómez^{1

4}

Affiliations

¹ Medical and Experimental Mycology Unit, Corporación para Investigaciones Biológicas (CIB), Medellín, Colombia.
² Hospital La Maria, Medellin, Colombia.
³ Mycotic Diseases Branch, Centers for Disease Control and Prevention, (CDC), Atlanta, United States.
⁴ School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia.

Abstract

A total of 23/45 (51%) patients with AIDS and histoplasmosis from Medellín, Colombia had other infections. Tuberculosis was the most common (n = 16/23, 70%). Pneumocystosis and cryptococcosis were found in three patients each (13%), bacterial infection and cytomegalovirus occurred each in two patients (9%) while toxoplasmosis, herpes virus and esophageal candidiasis were recorded in one patient each (4%). Of all co-infected patients, 18/23 (78%) had one, four (17%) had two and one (4%) had three additional opportunistic infections.

Keywords: AIDS; Co-infection; Histoplasma; Histoplasmosis.