[A Case of Breast Cancer with Local Recurrence in the Reconstructed Breast Tissue]

Gan To Kagaku Ryoho. 2017 Nov;44(12):1056-1058.
[Article in Japanese]

Abstract

The rate of local recurrence after mastectomy is reportedly similar to that of one-stage reconstruction. Most recurrences are in the skin or chest wall, while recurrence in the reconstructed breast is rare and the causes are uncertain. We report a case of a 42-year-old female who underwent partial mastectomy for left breast cancer with cT4aN0M1(PUL), cStage IV after endocrine therapy 3 years ago. Histopathological diagnosis was solid-tubular carcinoma. She had been treated with only endocrine therapy but diagnosed with local recurrence in the left breast. She underwent total mastectomy and rectus abdominis musculocutaneous flap reconstruction. Partial flap necrosis occurred following conservative therapy. She was accordingly treated with anastrozole and GnRH agonist. A mass approximately 1.5 cm in size was palpated inside of the reconstructed breast. As such, she was diagnosed with recurrence in the reconstructed breast through ultrasound biopsy. She underwent partial resection of the left precordial tumor, and histopathological examination revealed scirrhous cancer. She is currently well without any recurrence.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anastrozole
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / pathology
  • Breast Neoplasms / surgery*
  • Female
  • Gonadotropin-Releasing Hormone / agonists
  • Hormone Replacement Therapy
  • Humans
  • Mammaplasty*
  • Mastectomy
  • Multimodal Imaging
  • Neoplasm Invasiveness
  • Neoplasm Recurrence, Local / drug therapy
  • Neoplasm Recurrence, Local / surgery*
  • Nitriles / administration & dosage
  • Treatment Outcome
  • Triazoles / administration & dosage

Substances

  • Nitriles
  • Triazoles
  • Anastrozole
  • Gonadotropin-Releasing Hormone