A phase 1 dose-finding study of intravenous L-citrulline in sickle cell disease: a potential novel therapy for sickle cell pain crisis

Br J Haematol. 2019 Feb;184(4):634-636. doi: 10.1111/bjh.15124. Epub 2018 Feb 7.

¹ Division of Hematology, Children's National Medical Center, George Washington School of Medicine and Health Sciences, Washington, DC, USA.
² Department of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi, USA.
³ Departments of Physiology & Pharmacology and Medicine, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Canada.
⁴ Children's Hospital of Philadelphia, Philadelphia, PA, USA.
⁵ Division of Genetics, Children's National Medical Center, Washington, DC, USA.

No abstract available

Keywords: citrulline; pharmacokinetic; sickle.

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