Leadless Pacemakers: State of the Art and Future Perspectives

Domenico G Della Rocca; Carola Gianni; Luigi Di Biase; Andrea Natale; Amin Al-Ahmad

doi:10.1016/j.ccep.2017.11.003

Leadless Pacemakers: State of the Art and Future Perspectives

Card Electrophysiol Clin. 2018 Mar;10(1):17-29. doi: 10.1016/j.ccep.2017.11.003.

Authors

Domenico G Della Rocca¹, Carola Gianni¹, Luigi Di Biase², Andrea Natale³, Amin Al-Ahmad⁴

Affiliations

¹ Texas Cardiac Arrhythmia Institute, St. David's Medical Center, 3000 North IH-35, Suite 720, Austin, TX 78705, USA.
² Texas Cardiac Arrhythmia Institute, St. David's Medical Center, 3000 North IH-35, Suite 720, Austin, TX 78705, USA; Albert Einstein College of Medicine, Montefiore Hospital, Bronx, NY, USA; Department of Biomedical Engineering, Cockrell School of Engineering, University of Texas, Austin, TX, USA; Department of Cardiology, University of Foggia, Foggia, Italy.
³ Texas Cardiac Arrhythmia Institute, St. David's Medical Center, 3000 North IH-35, Suite 720, Austin, TX 78705, USA; Department of Biomedical Engineering, Cockrell School of Engineering, University of Texas, Austin, TX, USA; Department of Internal Medicine, Dell Medical School, University of Texas, Austin, TX, USA; Interventional Electrophysiology, Scripps Clinic, La Jolla, CA, USA; Department of Cardiology, MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA; Division of Cardiology, Stanford University, Stanford, CA, USA; Atrial Fibrillation and Arrhythmia Center, California Pacific Medical Center, San Francisco, CA, USA.
⁴ Texas Cardiac Arrhythmia Institute, St. David's Medical Center, 3000 North IH-35, Suite 720, Austin, TX 78705, USA. Electronic address: [email protected].

PMID: 29428139
DOI: 10.1016/j.ccep.2017.11.003

Abstract

Leadless pacemaker therapy is a new technology that aims at avoiding lead- and pocket-related complications of conventional transvenous and epicardial pacing. To date, 2 self-contained leadless pacemakers for right ventricular pacing have been clinically available: the Nanostim Leadless Pacemaker System and the Micra Transcatheter Pacing System. Additionally, a new multicomponent leadless pacemaker for endocardial left ventricular pacing has been proposed as an alternative choice for cardiac resynchronization therapy. In this review, we describe the state of the art of leadless pacing and compare the currently available devices with traditional transvenous leadless pacemakers.

Keywords: Bradyarrhythmias; Cardiac arrhythmias; Cardiac pacing; Cardiac resynchronization therapy; Leadless pacemaker; Transvenous leads; Transvenous pacemaker.

Publication types

Review

MeSH terms

Arrhythmias, Cardiac / therapy*
Cardiac Resynchronization Therapy / methods*
Equipment Design
Heart Ventricles
Humans
Pacemaker, Artificial*