Shedding Light on IDH1 Mutation in Gliomas

Clin Cancer Res. 2018 Jun 1;24(11):2467-2469. doi: 10.1158/1078-0432.CCR-18-0011. Epub 2018 Feb 13.

Abstract

IDH mutation is of central importance in the diagnosis and treatment of gliomas. Fourier-transform infrared spectroscopy, in combination with a supervised machine-learning approach, can be used to detect metabolic alterations induced by IDH1 mutations in a fraction of the time of conventional techniques. Clin Cancer Res; 24(11); 2467-9. ©2018 AACRSee related article by Uckermann et al., p. 2530.

Publication types

  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Glioma*
  • Humans
  • Isocitrate Dehydrogenase / genetics*
  • Mutation
  • Spectrum Analysis

Substances

  • Isocitrate Dehydrogenase
  • IDH1 protein, human