DNA methylation modules in airway smooth muscle are associated with asthma severity

Eur Respir J. 2018 Apr 12;51(4):1701068. doi: 10.1183/13993003.01068-2017. Print 2018 Apr.

¹ School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, UK.
² MRC and Asthma UK Centre in Allergic Mechanisms of Asthma, Kings College London, London, UK.
³ Discovery Science Group, Dept of Computing, Imperial College London, London, UK.
⁴ Epigenetics Unit, Dept of Surgery and Cancer, Imperial College London, London, UK.
⁵ Airways Disease, National Heart and Lung Institute, Imperial College, London and Royal Brompton NIHR Biomedical Research Unit, London, UK.

Abstract

Abnormal DNA methylation patterns distinguish airway smooth muscle cell function in asthma and asthma severity http://ow.ly/cTrK30iCwVK