Mutational profiling of isolated myeloid sarcomas and utility of serum 2HG as biomarker of IDH1/2 mutations

Leukemia. 2018 Sep;32(9):2008-2081. doi: 10.1038/s41375-018-0056-6. Epub 2018 Feb 26.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Biomarkers
  • Biopsy
  • DNA Mutational Analysis
  • Female
  • Glutarates / blood*
  • Humans
  • Isocitrate Dehydrogenase / genetics*
  • Male
  • Middle Aged
  • Mutation*
  • Positron-Emission Tomography
  • Sarcoma, Myeloid / blood*
  • Sarcoma, Myeloid / diagnosis
  • Sarcoma, Myeloid / genetics*
  • Young Adult

Substances

  • Biomarkers
  • Glutarates
  • alpha-hydroxyglutarate
  • IDH2 protein, human
  • Isocitrate Dehydrogenase
  • IDH1 protein, human