Emerging Molecular Imaging Techniques in Gynecologic Oncology

PET Clin. 2018 Apr;13(2):289-299. doi: 10.1016/j.cpet.2017.11.011. Epub 2018 Jan 10.

Abstract

Molecular imaging (mainly PET and MR imaging) has played important roles in gynecologic oncology. Emerging MR-based technologies, including DWI, CEST, DCE-MR imaging, MRS, and DNP, as well as FDG-PET and many novel PET radiotracers, will continuously improve practices. In combination with radiomics analysis, a new era of decision making in personalized medicine and precisely guided radiation treatment planning or real-time surgical interventions is being entered into, which will directly impact on patient survival. Prospective trials with well-defined endpoints are encouraged to evaluate the multiple facets of these emerging imaging tools in the management of gynecologic malignancies.

Keywords: Cervical cancer; Endometrial cancer; MR imaging; Molecular imaging; Ovarian cancer; PET; Radiomics; Vulvar cancer.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Female
  • Forecasting
  • Genital Neoplasms, Female / diagnostic imaging*
  • Genital Neoplasms, Female / pathology*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Middle Aged
  • Molecular Imaging / methods*
  • Molecular Imaging / trends
  • Neoplasm Invasiveness / pathology
  • Neoplasm Staging
  • Positron Emission Tomography Computed Tomography / methods*
  • Radiographic Image Enhancement*
  • Radiopharmaceuticals

Substances

  • Radiopharmaceuticals