Interim estimate of influenza vaccine effectiveness in hospitalised children, Hong Kong, 2017/18

Euro Surveill. 2018 Feb;23(8):18-00062. doi: 10.2807/1560-7917.ES.2018.23.8.18-00062.

Abstract

We conducted a hospital-based test-negative study in Hong Kong to estimate influenza vaccine effectiveness (VE) for the winter of 2017/18. The interim analysis included data on 1,078 children admitted between 4 December 2017 and 31 January 2018 with febrile acute respiratory illness and tested for influenza. We estimated influenza VE at 66% (95% confidence interval (CI): 43-79) overall, and 65% (95% CI: 40-80) against influenza B, the dominant virus type (predominantly B/Yamagata).

Keywords: influenza virus; public health; test negative design; vaccine effectiveness; vaccines and immunisation; viral infections.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Child, Preschool
  • Female
  • Hong Kong / epidemiology
  • Hospitalization / statistics & numerical data*
  • Humans
  • Infant
  • Influenza A virus / immunology
  • Influenza A virus / isolation & purification*
  • Influenza B virus / immunology
  • Influenza B virus / isolation & purification*
  • Influenza Vaccines / administration & dosage*
  • Influenza Vaccines / immunology
  • Influenza, Human / diagnosis*
  • Influenza, Human / epidemiology
  • Influenza, Human / prevention & control
  • Male
  • Public Health Surveillance
  • Seasons
  • Vaccination*
  • Vaccine Potency

Substances

  • Influenza Vaccines