[The peculiar features of the microbial paysage and the problems of antibacterial therapy of the inflammatory ENT diseases in the patients presenting with diabetes mellitus]

Vestn Otorinolaringol. 2018;83(1):59-61. doi: 10.17116/otorino201883159-61.
[Article in Russian]

Abstract

This article is focused on the peculiar features of the ENT microbial paysage in the patients presenting with diabetes mellitus. We have examined a total of 310 patients including 145 suffering from the pyoinflammatory ENT diseases and concomitant diabetes mellitus. The study has demonstrated that the microbial biocenoses of the ENT organs in the diabetic patients are dominated by the potentially pathogenic and transitory microflora whereas the saccharolytic microflora and the non-fermentative bacteria (pseudomonades) concentrate in the foci of ENT inflammation. The spectrum of microorganism that occur in the areas of inflammation are shown to depend on the quality of compensation of diabetes mellitus.

Рассмотрены особенности микробного пейзажа ЛОР-органов у больных сахарным диабетом. Обследованы 310 пациентов, среди которых 145 больных с гнойно-воспалительными заболеваниями ЛОР-органов и сопутствующим сахарным диабетом (СД). Установлено, что в микробных биоценозах ЛОР-органов у больных СД преобладает условно-патогенная и транзиторная микрофлора, в очагах воспаления ЛОР-органов - сахаролитическая микрофлора и неферментирующие бактерии (псевдомонады). Установлена зависимость спектра микроорганизмов в очагах воспаления от степени компенсации СД.

Keywords: ENT organs; inflammation; microflora; non-fermentative bacteria.

MeSH terms

  • Bacteria* / classification
  • Bacteria* / isolation & purification
  • Bacteria* / pathogenicity
  • Biota
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetes Mellitus, Type 1 / diagnosis
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetes Mellitus, Type 2 / diagnosis
  • Female
  • Humans
  • Male
  • Microbiological Techniques
  • Middle Aged
  • Nasopharynx / microbiology*
  • Opportunistic Infections* / complications
  • Opportunistic Infections* / etiology
  • Opportunistic Infections* / microbiology
  • Otorhinolaryngologic Diseases* / classification
  • Otorhinolaryngologic Diseases* / complications
  • Otorhinolaryngologic Diseases* / etiology
  • Otorhinolaryngologic Diseases* / microbiology