A counseling framework for moderate-penetrance colorectal cancer susceptibility genes

Genet Med. 2018 Nov;20(11):1324-1327. doi: 10.1038/gim.2018.12. Epub 2018 Mar 1.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenomatous Polyposis Coli Protein / genetics
  • Adult
  • Checkpoint Kinase 2 / genetics
  • Colorectal Neoplasms / diagnosis*
  • Colorectal Neoplasms / genetics*
  • Colorectal Neoplasms / pathology
  • DNA Glycosylases / genetics
  • Female
  • Genetic Counseling / methods*
  • Genetic Predisposition to Disease
  • Humans
  • Male
  • Middle Aged
  • Mutation
  • Neoplasm Proteins / genetics
  • Penetrance*

Substances

  • APC protein, human
  • Adenomatous Polyposis Coli Protein
  • Neoplasm Proteins
  • Checkpoint Kinase 2
  • CHEK2 protein, human
  • DNA Glycosylases
  • mutY adenine glycosylase