The relationship between preoperative nutritional state and adverse outcome following abdominal and thoracic surgery in children: Results from the NSQIP database

J Pediatr Surg. 2018 May;53(5):1046-1051. doi: 10.1016/j.jpedsurg.2018.02.008. Epub 2018 Feb 7.

Abstract

Introduction: Anthropometric measurements can be used to define pediatric malnutrition. Our study aims to: (1) characterize the preoperative nutritional status of children undergoing abdominal or thoracic surgery, and (2) describe the associations between WHO-defined acute (stunting) and chronic (wasting) undernutrition (Z-scores <-2) and obesity (BMI Z-scores >+2) with 30-day postoperative outcomes.

Methods: We queried the Pediatric NSQIP Participant Use File and extracted data on patients' age 29days to 18years who underwent abdominal or thoracic procedures. Normalized anthropometric measures were calculated, including weight-for-height for <2years, BMI for ages ≥2years, and height for age. Logistic regression models were developed to assess nutritional outlier status as an independent predictor of postoperative outcome.

Results: 23,714 children (88% ≥2y) were evaluated. 4272 (18%) were obese, while 2640 (11.1%) and 904 (3.8%) were stunted and wasted, respectively, after controlling for gender, ASA/procedure/wound classification, preoperative steroid use, need for preoperative nutritional support, and obese children had higher odds of SSIs (OR 1.29, 95% CI 1.1-1.5, p=0.001), while stunted children were at increased risk of any 30-day postoperative complication (OR 1.16, 95% CI 1.0-1.3, p=0.036).

Conclusion: Children who are stunted or obese are at increased risk of adverse outcome after abdominal or thoracic surgery.

Level of evidence: III.

Keywords: Anthropometry; Children; Malnutrition; NSQIP; Obesity; Outcomes; Risk-adjustment; Surgery.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Body Mass Index
  • Child
  • Child Nutrition Disorders / complications*
  • Child Nutrition Disorders / epidemiology
  • Child, Preschool
  • Digestive System Surgical Procedures / adverse effects*
  • Female
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Male
  • Nutritional Status*
  • Obesity / complications*
  • Obesity / epidemiology
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / etiology
  • Preoperative Period
  • Registries*
  • Risk Assessment
  • Risk Factors
  • Thoracic Surgical Procedures / adverse effects*
  • United States / epidemiology