Hemorrhagic fever with renal syndrome accompanied by panhypopituitarism and central diabetes insipidus: a case report

Hee Jung Ahn; Jong-Hoon Chung; Dong-Min Kim; Na-Ra Yoon; Choon-Mee Kim

doi:10.1007/s13365-018-0624-6

Hemorrhagic fever with renal syndrome accompanied by panhypopituitarism and central diabetes insipidus: a case report

J Neurovirol. 2018 Jun;24(3):382-387. doi: 10.1007/s13365-018-0624-6. Epub 2018 Mar 5.

Authors

Hee Jung Ahn¹, Jong-Hoon Chung¹, Dong-Min Kim², Na-Ra Yoon¹, Choon-Mee Kim³

Affiliations

¹ Department of Internal Medicine, College of Medicine, Chosun University, 588 Seosuk-dong, Dong-gu, Gwangju, 61453, Republic of Korea.
² Department of Internal Medicine, College of Medicine, Chosun University, 588 Seosuk-dong, Dong-gu, Gwangju, 61453, Republic of Korea. [email protected].
³ Premedical Science, College of Medicine, Chosun University, Gwangju, Republic of Korea.

PMID: 29508304
DOI: 10.1007/s13365-018-0624-6

Abstract

Central diabetes insipidus (DI) was detected in a patient with hemorrhagic fever with renal syndrome (HFRS) who had been molecularly and serologically diagnosed with Hantaan virus infection. We recommend that clinicians differentiate central DI in HFRS patients with a persistent diuretic phase even when pituitary MRI findings are normal.

Keywords: Diabetes insipidus; Hantaan virus; Hypopituitarism; Viral hemorrhagic fevers.

Publication types

Case Reports

MeSH terms

Deamino Arginine Vasopressin / therapeutic use
Diabetes Insipidus, Neurogenic / diagnostic imaging
Diabetes Insipidus, Neurogenic / metabolism
Diabetes Insipidus, Neurogenic / physiopathology*
Diabetes Insipidus, Neurogenic / virology
Hantaan virus / classification
Hantaan virus / genetics*
Hantaan virus / isolation & purification
Hemorrhagic Fever with Renal Syndrome / diagnostic imaging
Hemorrhagic Fever with Renal Syndrome / metabolism
Hemorrhagic Fever with Renal Syndrome / physiopathology*
Hemorrhagic Fever with Renal Syndrome / virology
Humans
Hypopituitarism / diagnostic imaging
Hypopituitarism / metabolism
Hypopituitarism / physiopathology*
Hypopituitarism / virology
Magnetic Resonance Imaging
Male
Middle Aged
Phylogeny
Thyroxine / therapeutic use

Substances

Deamino Arginine Vasopressin
Thyroxine

Supplementary concepts

Combined Pituitary Hormone Deficiency