An Overview on Diabetic Foot Infections, including Issues Related to Associated Pain, Hyperglycemia and Limb Ischemia

Curr Pharm Des. 2018;24(12):1243-1254. doi: 10.2174/1381612824666180302145754.

Abstract

Factors strongly related to the risk of developing diabetic foot infections include vascular, neuropathic and hyperglycemic complications of long-standing diabetes mellitus. These infections are common and serious, posing a worldwide burden on administrative providers of healthcare, patients and physicians. The most appropriate approach to these infections is with a multidisciplinary team. This subchapter summarizes the current state-of the-art concerning therapy, and scientific knowledge, for peripheral arterial insufficiency, hyperglycemia, and peripheral neuropathy of the diabetic foot, with an emphasis on the infectious complications.

Keywords: Diabetic foot infection; diabetes mellitus; hyperglycemia; ischemia; pain; peripheral neuropathy..

Publication types

  • Review

MeSH terms

  • Diabetic Foot / complications
  • Diabetic Foot / diagnostic imaging
  • Diabetic Foot / drug therapy*
  • Diabetic Foot / physiopathology*
  • Humans
  • Hyperglycemia / diagnostic imaging
  • Hyperglycemia / drug therapy
  • Hyperglycemia / etiology*
  • Ischemia / diagnostic imaging
  • Ischemia / drug therapy
  • Ischemia / etiology*
  • Pain / diagnostic imaging
  • Pain / drug therapy
  • Pain / etiology*