Acquired Chiari I Malformation Secondary to Spontaneous Intracranial Hypotension Syndrome and Persistent Hypoglycemia: A Case Report

J Clin Res Pediatr Endocrinol. 2018 Nov 29;10(4):391-394. doi: 10.4274/jcrpe.0042. Epub 2018 Feb 27.

Abstract

Spontaneous intracranial hypotension (SIH) is a rare and potentially serious condition in childhood. Cerebrospinal fluid (CSF) volume depletion is thought to be the main causative feature for intracranial hypotension and results from a spontaneous CSF leak, often at the spine level. SIH is increasingly diagnosed in clinical practice, although it manifests a varied symptomatology. The downward displacement of the brain, sometimes mimicking a Chiari I malformation, has rarely been reported. We present a case of a SIH with Chiari I malformation accompanied by an unusual clinical presentation of persistent hypoglycemia.

Keywords: Intracranial hypotension; hypoglycemia; vagotomy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Arnold-Chiari Malformation / diagnosis*
  • Arnold-Chiari Malformation / etiology
  • Cerebrospinal Fluid Leak / complications
  • Cerebrospinal Fluid Leak / diagnosis*
  • Diagnosis, Differential
  • Female
  • Humans
  • Hypoglycemia / complications
  • Hypoglycemia / diagnosis*
  • Intracranial Hypotension / complications
  • Intracranial Hypotension / diagnosis*
  • Syndrome