The classroom microbiome and asthma morbidity in children attending 3 inner-city schools

Peggy S Lai; Raivo Kolde; Eric A Franzosa; Jonathan M Gaffin; Sachin N Baxi; William J Sheehan; Diane R Gold; Dirk Gevers; Ramnik J Xavier; Wanda Phipatanakul

doi:10.1016/j.jaci.2018.02.022

The classroom microbiome and asthma morbidity in children attending 3 inner-city schools

J Allergy Clin Immunol. 2018 Jun;141(6):2311-2313. doi: 10.1016/j.jaci.2018.02.022. Epub 2018 Mar 5.

Authors

Affiliations

¹ Massachusetts General Hospital, Boston, Mass; Harvard T.H. Chan School of Public Health, Boston, Mass; Harvard Medical School, Boston, Mass.
² Massachusetts General Hospital, Boston, Mass.
³ Harvard T.H. Chan School of Public Health, Boston, Mass.
⁴ Harvard Medical School, Boston, Mass; Boston Children's Hospital, Boston, Mass.
⁵ Harvard T.H. Chan School of Public Health, Boston, Mass; Harvard Medical School, Boston, Mass; Brigham and Women's Hospital, Boston, Mass.
⁶ Broad Institute of MIT and Harvard University, Cambridge, Mass.
⁷ Massachusetts General Hospital, Boston, Mass; Harvard Medical School, Boston, Mass; Broad Institute of MIT and Harvard University, Cambridge, Mass.
⁸ Harvard Medical School, Boston, Mass; Broad Institute of MIT and Harvard University, Cambridge, Mass. Electronic address: [email protected].

Abstract

The classroom microbiome is different from the home microbiome. Higher classroom microbial diversity is associated with increased asthma symptoms. In this pilot study, a school-level integrated pest management intervention changed the classroom microbiome.

Publication types

Letter
Randomized Controlled Trial
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Air Filters
Air Pollution, Indoor / adverse effects*
Asthma / epidemiology*
Asthma / etiology
Child
Female
Humans
Male
Microbiota*
Morbidity
Pilot Projects
Schools*
Urban Population

Abstract

Publication types

MeSH terms

Grants and funding