1 From the Division of Trauma, Surgical Critical Care and Emergency Surgery (N.M., J.L.P.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Critical Care and Hyperbaric Medicine (D.T.C.), VCA Regional Institute for Veterinary Emergencies and Referrals, Chattanooga, Tennessee; Department of Surgery (C.T.), Indiana University School of Medicine, Indianapolis; Terre Haute Regional Hospital (C.T.), Terre Haute, Indiana; Department of Anesthesiology and Critical Care (M.F.C.), and Section of Medical Critical Care, Department of Medicine, Perelman School of Medicine (M.M.), University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.